Balancer is an action adventure story, with the twist that the beautiful heroine is in fact a little old lady who is able to transform into a supermodel. It looks like great fun.
Karuizawa Syndrome is altogether stranger. Even with so much manga now under the bridge it still looks odd. The art style varies from realistic to chibi so much the characters bounce up and down like yoyos, sometimes even in the same panel. It appears to follow a group of characters who are possibly early twenties, though they spend so much time in chibi mode it's hard to tell. They drive hyper realistic cars and motorbikes, have chibi sex, and a couple of them seem to be nazis.
As far as I know neither of these series have ever been translated. But I guess neither exactly fit into what american publishers look for in a manga.